Río Lagartos is a town in the state of Yucatán, Mexico. The town lies 42 kilometres north of Tizimín. Río Lagartos is located at a lagoon, the Ria Lagartos, which is part of a natural reserve. This lagoon is part of the Petenes mangroves ecoregion, and the Ria Lagartos has been designated as an internationally recognized important bird area.